Directly observed therapy (DOT) for tuberculosis: why, when, how and if?
نویسندگان
چکیده
منابع مشابه
Directly observed therapy (DOT) for tuberculosis: why, when, how and if?
Background. Tuberculosis is a major public health problem in South Africa, made worse by poor adherence to and frequent interruption of treatment. Direct observation (DO) of tuberculosis patients taking their drugs is supposed to improve treatment completion and outcome. We compared DO with self-supervision, in which patients on the same drug regimen are not observed taking their pills, to asse...
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BACKGROUND Directly observed therapy (DOT) is a widely recommended and promoted strategy to manage tuberculosis (TB), however, there is still disagreement about the role of DOT in TB control and the impact it has on reducing the acquisition and transmission of drug resistant TB. This study compares the portion of drug resistant genotype clusters, representing recent transmission, within and bet...
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BACKGROUND Tuberculosis (TB) requires at least six months of treatment. If treatment is incomplete, patients may not be cured and drug resistance may develop. Directly Observed Therapy (DOT) is a specific strategy, endorsed by the World Health Organization, to improve adherence by requiring health workers, community volunteers or family members to observe and record patients taking each dose. ...
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1 Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America, 2 Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University Medical Center, New York, New York, United States of America, 3 Massachusetts General Hospital, Harvard Medical School, Harvard School of...
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ژورنال
عنوان ژورنال: Thorax
سال: 1999
ISSN: 0040-6376
DOI: 10.1136/thx.54.2008.s42